The pharmacy company that makes Avandia knew more than a decade ago that the blockbuster diabetes drug caused an increased risk of heart problems but covered up the information, according to a report published Tuesday in The New York Times.
In a 1999 trial pitting Avandia against its competitor, Actos, the drug company, then known as [...]
A common pain reliever may help people with type 2 diabetes control their blood sugar levels.
A preliminary study shows salsalate reduced blood sugar levels and helped with glycemic control at a variety of doses in people with type 2 diabetes. However, it also has been shown to increase protein in the urine and its long-term [...]
US drugmakers Pfizer Inc and Nektar Therapeutics on Wednesday warned of cases of lung cancer in clinical trials of their inhaled insulin Exubera.
The findings led Nektar to announce it was abandoning its search for a new marketing partner for the troubled drug, effectively signaling Exubera’s demise after entering the market in January 2006.
Pfizer, the world’s [...]
For people with type 2 diabetes and moderately elevated blood glucose levels, the medication vildagliptin, sold under the brand name Galvus, can produce long-term improvements in the functioning of the insulin-secreting beta cells in the pancreas along with better glucose control, researchers report.
“Improvement of glucose control, which was a known fact for vildagliptin, is paralleled, [...]
Treatment with metformin or lifestyle changes promoting exercise and a healthy diet are both effective in reversing the weight gain associated with antipsychotic medications, according to a clinical trial conducted in China. However, a combination of the two approaches is even better.
Metformin, sold under various trade names such as Glucophage, is primarily used to lower [...]
The findings of clinical trials have linked the use of thiazolidinediones, a class of diabetes drugs, with congestive heart failure and possibly heart attacks. Now, new research indicates that these associations, at least with Avandia, also apply to individuals in the community, and not just clinical trials.
Dr. Lorraine L. Lipscombe, from the Institute for Clinical [...]
